Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal

Stephan Busque, John D. Scandling, Robert Lowsky, Judith Shizuru, Kent Jensen, Jeffrey Waters, Hsin-Hsu Wu, Kevin Sheehan, Asha Shori, Okmi Choi, Thomas Pham, Marcelo A. Fernandez Vina, Richard Hoppe, John Tamaresis, Philip Lavori, Edgar G. Engleman, Everett Meyer and Samuel Strober
Science Translational Medicine 2020, Volume 12, Issue 528

Macrochimerism and Clinical Transplant Tolerance

John D. Scandling, Stephan Busque, Robert Lowsky, Judith Shizuru, Asha Shori, Edgar Engleman, Kent Jensen, Samuel Strober
Human Immunology 2018, Volume 79, Issue 5, Pages 266-271

Review of different chimerism approaches to achieve immune tolerance.

Induction of Tolerance through Mixed Chimerism

David H. Sachs, Tatsuo Kawai, and Megan Sykes
Cold Spring Harb Perspect Med 2014; 4:a015529

A broad review of immune tolerance in organ transplant.

Use of hematopoietic cell transplants to achieve tolerance in patients with solid organ transplants

Samuel Strober
Blood 2016 127:1539-1543

Review of immune tolerance approaches at multiple clinical centers.

Chimerism, Graft Survival, and Withdrawal of Immunosuppressive Drugs in HLA Matched and Mismatched Patients After Living Donor Kidney and Hematopoietic Cell Transplantation

J. D. Scandling, S. Busque, J. A. Shizuru, R. Lowsky, R. Hoppe, S. Dejbakhsh-Jones, K. Jensen, A. Shori, J. A. Strober, P. Lavori, B. B. Turnbull, E. G. Engleman, S. Strober
American Journal of Transplantation 2015; 15: 695-704

Snapshot of the Stanford clinical experience with 2014 data cutoff (prior to success with HLA-mismatched patients).

Firmly Tilting the Balance of Clinical Transplant Immunity Toward Tolerance

Volume 15, Issue 3, pages 583–584, March 2015

Editorial for Scandling 2015 publication.

Tolerance and Withdrawal of Immunosuppressive Drugs in Patients Given Kidney and Hematopoietic Cell Transplants

John D. Scandling, Stephan Busque, Sussan Dejbakhsh-Jones, Claudia Benike, Minnie Sarwal, Maria T. Millan, Judith A. Shizuru, Robert Lowsky, Edgar G. Engleman, and Samuel Strober
Am J Transplant 2012 May; 12(5): 1133-1145

Interim publication on Stanford experience with HLA-matched patients.

Immune Tolerance to Combined Organ and Bone Marrow Transplants After Fractionated Lymphoid Irradiation Involves Regulatory NK T Cells and Clonal Deletion

Masanori Higuchi, Defu Zeng, Judith Shizuru, Jennifer Gworek, Sussan Dejbakhsh-Jones, Masaru Taniguchi and Samuel Strober
J Immunol 2002; 169:5564-5570

Mechanism of action publication.

Translational Studies in Hematopoietic Cell Transplantation: Treatment of Hematologic Malignancies as a Stepping Stone to Tolerance Induction

Samuel Strober, Thomas R. Spitzer, Robert Lowsky, and Megan Sykes
Semin Immunol. 2011 Aug; 23(4): 273–281

Most comprehensive review of preclinical studies of immune tolerance.
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